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Recipharm to develop two inhalation formulations for Transpire Bio

Florida-based startup Transpire Bio announced that it has signed an agreement with Recipharm for development of two inhaled candidates, TRB-1 and TRB-2, for the treatment of asthma and COPD. The company says that the two generic MDIs are "intended for advanced markets." Transpire CEO Xian-Ming Zeng said, "Our mission is to improve access to important, life-saving … [Read more...] about Recipharm to develop two inhalation formulations for Transpire Bio

VisionHealth says Boehringer Ingelheim to cooperate on distribution of the Kata inhaler training app in Germany

German digital health company VisionHealth has announced that it will "cooperate on distribution of inhalation platform Kata" with Boehringer Ingelheim in Germany. The Kata app uses artificial intelligence and augmented reality technology in conjunction with the patient's smartphone camera to provide interactive inhaler use coaching. The company says that the app can … [Read more...] about VisionHealth says Boehringer Ingelheim to cooperate on distribution of the Kata inhaler training app in Germany

Theravance, Innoviva selling Trelegy Ellipta royalty interests to Royalty Pharma

According to Theravance Biopharma, the company is selling its stake in Theravance Respiratory Company (TRC), which received royalties from sales of GSK's Trelegy Ellipta fluticasone furoate / umeclidinium / vilanterol DPI. The deal with Royalty Pharma is worth up to $1.5 billion, including $1.1 billion up front, the company said. Theravance Biopharma owns 85% of TRC; … [Read more...] about Theravance, Innoviva selling Trelegy Ellipta royalty interests to Royalty Pharma

Glenmark and SaNOtize publish positive results from Phase 3 trial of nitric oxide nasal spray for COVID-19

Glenmark Pharmaceuticals and SaNOtize have announced the publication of results from a Phase 3 clinical trial of NONS nitric oxide nasal spray for the treatment of COVID-19 in The Lancet Regional Health Southeast Asia. SaNOtize announced initiation of the Phase 3 trial in June 2021, and Glenmark announced in August 2021 that it had acquired the rights to NONS in India … [Read more...] about Glenmark and SaNOtize publish positive results from Phase 3 trial of nitric oxide nasal spray for COVID-19

Pulmatrix initiates Phase 1 trial of PUR3100 inhaled dry powder DHE

Pulmatrix said that the first subjects have been dosed in a Phase 1 trial of the company's PUR3100 dry powder dihydroergotamine (DHE), which is based on Pulmatrix's iSPERSE particle engineering platform. The company announced in March 2021 that it intended to develop the PUR3100 DPI for the treatment of migraines. The Phase 1 trial is expected to enroll 24 healthy … [Read more...] about Pulmatrix initiates Phase 1 trial of PUR3100 inhaled dry powder DHE

NurExone partners with Polyrizon for development of intranasal therapy for spinal cord injuries

Israeli startup NurExone Biologic has announced that it will pay Israeli nasal delivery specialist Polyrizon a total of up to $3,350,000 for development of an intranasal formulation of NurExone's ExoTherapy, exosomes loaded with modified siRNA sequences for the treatment of traumatic spinal cord injuries. The formulation will be based on Polyrizon's Trap and Target … [Read more...] about NurExone partners with Polyrizon for development of intranasal therapy for spinal cord injuries

RS BioTherapeutics reports positive preclinical results for its inhaled CBDa

US-based startup RS BioTherapeutics has announced that a proof of concept study demonstrated that its RSBT-001 semi-synthetic cannabidiolic acid (CBDa) reduced but did not eliminate cytokines when dosed intranasally at 1 mg/kg in a mouse model of pulmonary inflammation. The study was conducted by researchers at Marshall University. RS BioTherapeutics licensed the … [Read more...] about RS BioTherapeutics reports positive preclinical results for its inhaled CBDa