Serendex Pharmaceuticals has announced that data from a Phase 1 randomized, double blind, placebo controlled single ascending dose/multiple ascending dose trial showed that Molgradex inhaled GM-CSF (molgramostim) was well tolerated at all dose levels. No serious or severe events were reported, and similar numbers of subjects in both the active and control groups … [Read more...] about Serendex announces positive topline data from Phase 1 study of Molgradex
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Phase 2 data show effectiveness of Invion’s inhaled nadolol for smoking cessation
A Phase 2 study of Invion's INV102 inhaled nadolol showed that smokers using the therapy were much more likely to stop smoking or significantly reduce the number of cigarettes they smoked than those using a placebo, the company said. The randomized, double blinded, placebo controlled study also showed a significant reduction in biomarkers for the beta arrestin … [Read more...] about Phase 2 data show effectiveness of Invion’s inhaled nadolol for smoking cessation
Celdara Medical and Pulmatrix get grant for inhaled biologic for idiopathic pulmonary fibrosis
Celdara Medical and Pulmatrix have been awarded a 3-year $1.7 million Fast Track Small Business Innovation Research grant from the National Heart Lung and Blood Institute (NHLBI) for development of an inhaled therapy for the treatment of idiopathic pulmonary fibrosis, the companies said. A dry powder formulation of CM-YJH01, a biologic, will be developed using … [Read more...] about Celdara Medical and Pulmatrix get grant for inhaled biologic for idiopathic pulmonary fibrosis
Alexza Pharmaceuticals announces two promotions
Alexza Pharmaceuticals has promoted Catherine McAuliffe to VP, Operations and Stacy Palermini to VP, Finance, the company said. McAuliffe most recently served as Executive Director, Operations; the position of VP, Operations is newly created. Palermini was previously Executive Director, Finance. Alexza is developing several products using its Staccato inhalation … [Read more...] about Alexza Pharmaceuticals announces two promotions
GSK exercises option to develop inhaled drugs based on Liquidia’s PRINT technology
GlaxoSmithKline has exercised an option for an exclusive license to develop inhaled therapies using Liquidia Techonologies' PRINT particle engineering technology, Liquidia said. The option was included in a collaboration deal the two companies signed in 2012. Liquidia also said that it has retained the right to develop an inhaled therapy independently. Upon … [Read more...] about GSK exercises option to develop inhaled drugs based on Liquidia’s PRINT technology
Verona reports positive data from SAD/MAD trial of RPL554 for COPD
Verona Pharma has announce that data from the third part of single ascending dose (SAD)/multiple ascending dose (MAD) trial of nebulized RPL554 in COPD patients show that the formulation was well tolerated at all doses with no serious adverse events and that patients using RPL554 experienced "pronounced improvement in lung function." Verona reported results from … [Read more...] about Verona reports positive data from SAD/MAD trial of RPL554 for COPD
Hovione to more than double size, capacity of New Jersey facility
Hovione, which offers a wide range of inhalation drug development and manufacturing services, has announced that it will add 30,600 sq ft and a new commercial spray dryer to its East Windsor, NJ facility. The expansion will more than double the plant's size and capacity, and the company said that it expects to hire approximately 60 new employees to support the … [Read more...] about Hovione to more than double size, capacity of New Jersey facility
BI announces new data from Stiolto/Spiolto Respimat studies
Boehringer Ingelheim has announced new data from the ENERGITO and OTEMTO studies of the Stiolto tiotropium/olodaterol Respimat inhaler for the treatment of COPD. The FDA approved Stiolto Respimat in May 2015; in Europe, where the product is known as Spiolto Respimat, BI announced approval by several countries in July 2015. BI previously announced data from OTEMTO … [Read more...] about BI announces new data from Stiolto/Spiolto Respimat studies
Teva acquires Gecko Health Innovations
Teva Pharmaceutical has acquired privately held Gecko Health Innovations and its CareTRx asthma and COPD management system. CareTRx works with a monitoring device called GeckoCap that attaches to an MDI plus a mobile phone app. The acquisition comes two months after AstraZeneca announced a partnership with inhaler monitoring company Adherium. Gecko Founder and CEO … [Read more...] about Teva acquires Gecko Health Innovations
Additional positive Phase 3 results for OptiNose intranasal fluticasone
OptiNose has announced positive results from the NAVIGATE I Phase 3 trial of its OPN-375 intranasal fluticasone for the treatment of nasal polyposis demonstrating statistically significant reduction of symptoms and total polyp grade. In June 2015, the company announced positive results from the NAVIGATE II trial. Based on the results from both studies, OptiNose said, … [Read more...] about Additional positive Phase 3 results for OptiNose intranasal fluticasone