Inhalon Biopharma has announced the publication of two articles that present data from preclinical studies of the company's inhaled "muco-trapping" technologies. The first, published in the journal Advanced Science, describes a study of nebulized delivery of Inhalon's Mota-MT antibody to the lungs of nonatal lambs infected with RSV. The second article, published … [Read more...] about Inhalon publishes data from preclinical studies of its inhaled muco-trapping therapies in RSV and SARS-CoV-2 models
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AstraZeneca initiates 2 Phase 3 trials investigating the effects of Breztri Aerosphere MDI on cardiopulmonary factors and outcomes in COPD patients
AstraZeneca today announced the initiation of the Phase 3 ATHLOS and THARROS trials evaluating the effects of Breztri Aerosphere budesonide / glycopyrronium / formoterol fumarate MDI on cardiopulmonary parameters and outcomes (including death) in COPD patients. Breztri was approved by the FDA for the treatment of COPD in July 2020. In August 2023, the agency issued a … [Read more...] about AstraZeneca initiates 2 Phase 3 trials investigating the effects of Breztri Aerosphere MDI on cardiopulmonary factors and outcomes in COPD patients
MannKind presents data from Phase 4 trial of Afrezza inhaled insulin
MannKind Corporation announced that it recently presented initial data from a meal challenge that was part of the Phase 4 INHALE-3 trial of Afrezza insulin DPI plus basal insulin injections versus standard of care in Type 1 diabetics. Afrezza was approved by the FDA for the treatment of Type 1 and Type 2 diabetes in adults in 2014. The company said that it will … [Read more...] about MannKind presents data from Phase 4 trial of Afrezza inhaled insulin
Vast announces appointments in preparation for clinical development of ALX1 inhalation solution
Vast Therapeutics has announced the appointments of former Aradigm Senior Medical Director Paul Bruinenberg as Chief Medical Officer and Chris Polage as Medical Director in preparation for clinical development of its ALX1 inhalation solution. Bruinenberg was most recently Senior Medical Officer of the TB Alliance. In addition to his stint at Aradigm, Bruinenberg's … [Read more...] about Vast announces appointments in preparation for clinical development of ALX1 inhalation solution
Boehringer Ingelheim says it will limit out-of-pocket cost of its inhalers for some US patients
Boehringer Ingelheim said that "eligible patients" will pay no more than $35 per month for BI inhalers, including Atrovent HFA ipratropium MDI, Combivent Respimat ipratropium / albuterol SMI, Spiriva HandiHaler tiotropium DPI, Spiriva Respimat tiotropium SMI, Stiolto Respimat tiotropium / olodaterol SMI, and Striverdi Respimat olodaterol SMI. According to the company, … [Read more...] about Boehringer Ingelheim says it will limit out-of-pocket cost of its inhalers for some US patients
UWA researchers get A$500,000 grant for development of Spritz-OM probiotic nasal spray for ear infections
Researchers at the University of Western Australia have received a A$500,000 grant from the CUREator biotech incubator for development of the Spritz-OM probiotic nasal spray for the prevention of ear infections in children. The grant was one of 5 awarded recently as part of an effort to fund projects aimed at minimizing antimicrobial resistance. According to the … [Read more...] about UWA researchers get A$500,000 grant for development of Spritz-OM probiotic nasal spray for ear infections
Iconovo gets Innowide grant to support marketing activities in South Korea
Dry powder inhaler specialist Iconovo announced that the company has received a SEK 680,000 grant from the EU's Innowwide program that will fund a market study as part of Iconovo's plans to expand into the South Korean market. According to the company, the goal would initially be to attract South Korean customers for Iconovo's CDMO business and eventually licensing or … [Read more...] about Iconovo gets Innowide grant to support marketing activities in South Korea
Nocion raises $62 million for Phase 2b study of taplucainium DPI for the treatment of chronic cough
Nocion Therapeutics has announced that it raised $62 million in a Series B funding led by Monograph Capital and Arkin Bio Capital. Proceeds will be used to support a Phase 2b trial of its taplucainium (NTX-1175) inhaled dry powder for the treatment of chronic cough, the company said. In January 2020, Pulmatrix said that it had signed a deal to evaluate the use of … [Read more...] about Nocion raises $62 million for Phase 2b study of taplucainium DPI for the treatment of chronic cough
ARS Pharmaceuticals says Phase 2 trial of Neffy epinephrine nasal spray for urticaria met primary endpoints
ARS Pharmaceuticals announced that a Phase 2 trial of Neffy epinephrine nasal spray in patients with chronic spontaneous urticaria demonstrated that 1 mg and 2 mg doses of the intranasal epinephrine both produced statistically significant and clinically meaningful improvement in symptoms such as hives and itchy skin as soon as 5 minutes post dose. The inpatient study … [Read more...] about ARS Pharmaceuticals says Phase 2 trial of Neffy epinephrine nasal spray for urticaria met primary endpoints
Milestone says it will resubmit its NDA for etripamil nasal spray
Milestone Pharmaceuticals says that it held a Type A meeting with the FDA following receipt of a Refuse to File letter in December 2023 in response to the company's NDA for etripamil nasal spray for the treatment of paroxysmal supraventricular tachycardia (PSVT). According to Milestone, the agency did not request any additional clinical trials. The company says that … [Read more...] about Milestone says it will resubmit its NDA for etripamil nasal spray