Medical

According to AstraZeneca, data from the PATHOS real world study show fewer exacerbations and fewer hospitalizations for COPD patients treated with the Symbicort Turbuhaler than for those treated with Seretide (Advair). The study was published online in the Journal of Internal Medicine. The PATHOS study reviewed the medical records of 5,468 patients in Sweden who were … [Read more...] about AstraZeneca says study shows COPD treatment with budesonide/formoterol beats fluticasone/salmeterol

Acorda Therapeutics presented data from a Phase 1 study of its diazepam nasal spray at the American Academy of Neurology Annual Meeting this week showing that the plasma bioavailability of a 20 mg dose of diazepam nasal spray was comparable to that of a 20 mg dose of diazepam rectal gel. The company acquired the product, which is being developed for the treatment of … [Read more...] about Acorda Phase 1 data shows diazepam nasal spray has comparable biovailability to rectal gel

Upsher Smith presented positive Phase 1 data for its USL261 intranasal midazolam at the American Academy of Neurology (AAN) Meeting this week. The company launched a website to recruit patients for a Phase 3 study of the product last year. The intranasal formulation is being developed for the rescue treatment of seizures in epilepsy patients and is "intended to … [Read more...] about Upsher Smith presents positive Phase 1 data for intranasal midazolam

The first issue of the Lancet Respiratory Medicine journal is now available online and in print. Volume 1, Issue 1 includes articles on the efficacy of ICS/LABA combination inhalers and on the appropriateness of GOLD COPD categories among others. The issue includes a section called "Country in Focus," plus spotlights, comment, news, and 2012 research highlights … [Read more...] about The Lancet launches new respiratory medicine journal

A study published February 27, 2013 in PLOS ONE found that patients using the Asthmapolis remote inhaler monitoring system who received weekly email reports on their inhaler usage experienced significant reduction in symptoms and reported improved control. At the end of the study 75% of participants had achieved control of their asthma as measured by the the Asthma … [Read more...] about Study shows that use of Asthmapolis system improves asthma control

According to Critical Pharmaceuticals, a Phase 1b study has shown that its CP024 dry powder intranasal human growth hormone (hGH) was well tolerated with only a few minor adverse effects and showed a linear dose response. CP024 also induced production of therapeutic levels of insulin-like growth factor (IGF-1), making it the first nasal formulation of growth hormone … [Read more...] about Critical reports positive results for intranasal growth hormone study

California-based NEONC Technologies has announced plans for clinical trials of its NEO100 intranasal formulation of monoterpene perillyl alcohol (POH) for the treatment of gliomas and other CNS cancers. NEONC Chairman and CEO Thomas Chen, who is also Co-Director of the USC/Norris Neuro-Oncology Program and Professor of Neurological Surgery and Pathology at USC's Keck … [Read more...] about NEONC announces planned trial of intranasal therapy for brain cancer

An article posted online in Thorax on January 14, 2013 finds that children and teens who eat three or more servings of fast food per week have a significantly increased risk of severe asthma. The same fast food intake was also associated with increased risk of eczema and rhinitis, while fruit consumption was found to have an inverse association with severe asthma and … [Read more...] about Fast food consumption linked to severity of asthma, rhinitis in children