An article published in the March 17, 2011 issue of the New England Journal of Medicine details a study by researchers from the Boston University School of Medicine showing that omalizumab reduces the need for inhaled medications in inner-city children with asthma. Omalizumab is a monoclonal anti-IgE antibody. The 60-week randomized, double-blind study involved … [Read more...] about Omalizumab reduces need for inhaled asthma drugs
Medical
Phase 3 studies planned for nasal mist dental anesthesia
After a favorable end-of-Phase 2 meeting with the FDA, St. Renatus has announced that it plans to proceed to Phase 3 studies of its dental anesthetic, which is delivered as a nasal mist via a syringe. The nasally-administered anesthetic numbs the patient's teeth without numbing the face and lips. According to St. Renatus, the Phase 2 results showed that the nasal … [Read more...] about Phase 3 studies planned for nasal mist dental anesthesia
Phase 2 study of inhaled Bimosiamose produces positive results
German biopharmaceutical company Revotar has announced that its Bimosiamose inhalation solution for the treatment of COPD met its primary endpoint in a Phase 2 study involving more than 75 patients with moderate-to-severe COPD. Bimosiamose is a pan-selectin antagonist that the company is developing for asthma and acute lung injury in addition to COPD. According to … [Read more...] about Phase 2 study of inhaled Bimosiamose produces positive results
COPD named official COPD Foundation journal
The COPD Foundation has announced that COPD: Journal of Chronic Obstructive Pulmonary Disease will be its official journal. According to John W Walsh, President of the COPD Foundation, "COPD: Journal of Chronic Obstructive Pulmonary Disease, which offers an in-depth and easy-to-access array of research findings in this field, is an ideal partner for the Foundation." … [Read more...] about COPD named official COPD Foundation journal
Asthma and Allergy Foundation of America names “asthma capitals”
The Asthma and Allergy Foundation of America (AAFA) has published its annual list of US "asthma capitals," led this year by Richmond, Virginia. The list ranks 100 metropolitan areas in terms of difficulties that they present for asthma patients living in the area. Criteria for ranking the list include factors such as the prevalence of asthma in the area, the … [Read more...] about Asthma and Allergy Foundation of America names “asthma capitals”
Positive results for Verona lead candidate
A dosage trial of Verona Pharma's inhaled mixed phosphodiesterase (PDE) 3/4 inhibitor RPL554 for the treatment of mild asthma has demonstrated positive bronchodilation without any significant adverse effects at dosages two and four times higher than had been tested in a previous safety study. Verona is looking to license the drug or to find a partner for continued … [Read more...] about Positive results for Verona lead candidate
Review study supports inhaled epinephrine for croup
A review study published in The Cochrane Library finds that inhaled epinephrine provides significant relief of croup symptoms in children within 30 minutes compared to placebo. The review included 8 studies involving 225 children. Read the abstract. … [Read more...] about Review study supports inhaled epinephrine for croup
Positive Phase III results for Teva HFA nasal aerosol
Teva's Qnaze beclomethasone nasal aerosol has met all efficacy endpoints in a Phase III trial. The study involved 470 patients with perennial allergic rhinitis. After 6 weeks of treatment, patients using the product experienced significant reduction in nasal symptoms compared to those using a placebo spray. If approved, Qnaze will be the first non-aqueous intranasal … [Read more...] about Positive Phase III results for Teva HFA nasal aerosol
Successful test of inhaled measles vaccine
An article in the January 31, 2011 issue of PNAS describes how rhesus macaques gained protection against the measles virus after inhalation of a single dose of a dry powder live attenuated measles vaccine (LAMV). Two different DPIs, the PuffHaler and Solovent devices, were shown to be effective methods of delivery for the vaccine. Read the article. … [Read more...] about Successful test of inhaled measles vaccine
US asthma rate continues to increase
According to a new report by the National Center for Health Statistics of the US Center for Disease Control (CDC), the 2009 US asthma rate rose to 8.2% of the population, a historic high. The report includes data from several national surveys. Nearly 96% of patients surveyed reported that they had been taught how to use an inhaler. Read the complete report. … [Read more...] about US asthma rate continues to increase