Dutch vaccine developer Intravacc has announced that it will continue to develop its pipeline of intranasal vaccines while adding a contract development and manufacturing business. The company said that it will offer GMP manufacturing for clinical trials in addition to R&D services and expects to take on one or two contract projects per year. Intravacc's pipeline … [Read more...] about Intravacc to offer intranasal vaccine contract development services
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Theravance Biopharma restructures, will focus on respiratory drugs
Theravance Biopharma said that it expects to cut 270 jobs, or 75% of its current workforce, by February 2022 and that it will stop development of candidates outside of its respiratory portfolio. The announcement came just after the company announced the failure of a Phase 3 trial of its oral ampreloxetine. The company said that its R&D focus will now be on a label … [Read more...] about Theravance Biopharma restructures, will focus on respiratory drugs
ARS raises $55 million for potential launch of its Neffy intranasal epinephrine
ARS Pharmaceuticals said that it has raised $55 million in a Series D financing round to support approval and potential launch of its Neffy (ARS-1) intranasal epinephrine for the treatment of anaphylaxis as well as studies of the nasal spray for other indications. ARS submitted an MAA for Neffy to the EMA in November 2020. The FDA granted Fast Track designation … [Read more...] about ARS raises $55 million for potential launch of its Neffy intranasal epinephrine
Vivera gets US patents for Zicoh smart inhaler
Within one week in August, Vivera Pharmaceuticals has announced the issuance of two US patents covering its Zicoh smart inhaler technology. The first is US Patent No. 11,083,850 ("Secure smart dosing system with automated delivery, measurement, and management") and the second is US Patent No. 11,090,449 ("Smart inhaler device with automated dose delivery, measurement, … [Read more...] about Vivera gets US patents for Zicoh smart inhaler
Lupin launches Luforbec beclometasone/formoterol MDI in the UK
Lupin Healthcare has announced the launch of the Luforbec beclometasone/formoterol MDI in the UK. The generic version of Chiesi’s Fostair MDI was approved by the MHRA for the treatment of asthma and COPD in June 2021. According to Lupin, the Luforbec inhaler will be manufactured at the company's facilities in the US and India. The company cited UK prescribing data … [Read more...] about Lupin launches Luforbec beclometasone/formoterol MDI in the UK
Crystec and SignalRx partner on development of inhaled P13K-BRD4 inhibitor
Particle engineering company Crystec has announced a new partnership with SignalRx Pharmaceuticals for development of an inhaled dry powder formulation of SignalRx's SF2523 PI3K-BRD4 inhibitor for the treatment of pulmonary fibrosis, lung cancer, and COVID-19. The project is supported by Swiss life sciences investment company ADYA Consulting. According to the … [Read more...] about Crystec and SignalRx partner on development of inhaled P13K-BRD4 inhibitor
Cellics partners with HCmed on delivery of inhaled nanosponges
Nebulizer maker HCmed Innovations and Cellics Therapeutics have agreed to collaborate on inhaled delivery of cellular nanosponges as antibacterial and anti-inflammatory therapies. Cellics is currently developing nanosponges based on red blood cells and macrophages, and the company expects to advance its CTI-005 RBC nanosponge into clinical development for the … [Read more...] about Cellics partners with HCmed on delivery of inhaled nanosponges
Aptar Pharma gets option to acquire Pharmaxis’s Orbital DPI
Aptar Pharma will have 12 months to decide whether to exercise an exclusive option to acquire worldwide rights to Pharmaxis's high payload Orbital dry powder inhaler under a new agreement, the company said. The Orbital DPI, which can deliver up to 400 mg of powder in divided doses, was designed for delivery of Pharmaxis's Bronchitol inhaled mannitol, and Pharmaxis … [Read more...] about Aptar Pharma gets option to acquire Pharmaxis’s Orbital DPI
Philip Morris acquires Asprihale developer OtiTopic
Philip Morris International (PMI) has acquired inhaled drug developer OtiTopic, as "part of PMI’s strategic plan to leverage its expertise, scientific know-how, and capabilities in inhalation to grow a pipeline of inhaled therapeutics and respiratory drug delivery Beyond Nicotine," the company said. PMI recently announced a £1 billion offer for inhalation CDMO … [Read more...] about Philip Morris acquires Asprihale developer OtiTopic
Ji Xing acquires Chinese rights to two Oyster Point nasal sprays for dry eye
Ji Xing Pharmaceuticals has acquired Chinese development and commercialization rights to Oyster Point Pharma's OC-01 varenicline nasal spray and OC-02 simpinicline nasal spray for the treatment of dry eye disease in a deal that includes a $17.5 million upfront payment and up to $204.8 million in milestone payments and royalties. Earlier this year, Ji Xing acquired … [Read more...] about Ji Xing acquires Chinese rights to two Oyster Point nasal sprays for dry eye