CDMO Lonza has joined the International Pharmaceutical Aerosol Consortium on Regulation & Science (IPAC-RS), the company said. In the announcement of its IPAC-RS membership, Lonza specifically noted its planned participation in discussions related to particle engineering, inhaler testing, devices, and packaging. In July 2020, Lonza announced that it had … [Read more...] about Lonza joins IPAC-RS
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Sapigen Biologix gets funding from TDB for development of intranasal COVID-19 vaccine
The Indian Ministry of Science & Technology's Technology Development Board (TDB) has signed a development and commercialization agreement with Hyderabad-based Sapigen Biologix, committing ₹100 crores to development of a novel intranasal vaccine against COVID-19 and a vaccine against malaria, the ministry said. The ministry said that the TDB funding will cover … [Read more...] about Sapigen Biologix gets funding from TDB for development of intranasal COVID-19 vaccine
Harm Reduction Therapeutics gets additional $11 million for development of naloxone nasal spray
OxyContin maker Purdue Pharma will provide an additional $11 million to non-profit Harm Reduction Therapeutics (HRT) for continued development of HRT's HRT001 naloxone nasal spray for the reversal of opioid overdose. The additional funding was approved by the court overseeing Purdue's bankruptcy. Purdue began funding HRT in 2018, and in 2020, Purdue announced that it … [Read more...] about Harm Reduction Therapeutics gets additional $11 million for development of naloxone nasal spray
Virpax gets worldwide rights to Nanomerics’ AnQlar antiviral nasal spray
Virpax has announced an expansion of its license agreement with Nanomerics to add worldwide rights to AnQlar nasal spray, an antiviral mucoadhesive polymer derived from chitosan. The original license agreement, which was announced in August 2020, included North American rights only. According to Nanomerics, the additional funds paid by Virpax for the expanded license … [Read more...] about Virpax gets worldwide rights to Nanomerics’ AnQlar antiviral nasal spray
Impel Neuropharma secures $100 million for continued commercialization of Trudhesa nasal spray
Funds managed by Oaktree Capital Management will provide $100 million in funding to Impel NeuroPharma, with $50 million of that amount in cash up front as part of a royalty agreement on net sales of Trudhesa dihydroergotamine (DHE) nasal spray and the other $50 million in the form of a credit facility. The FDA approved Trudhesa for the treatment of migraine in … [Read more...] about Impel Neuropharma secures $100 million for continued commercialization of Trudhesa nasal spray
Consortium partners with RocketVax on intranasal COVID-19 vaccine development
A Swiss-German consortium led by Volker Thiel of the Institute of Virology and Immunology and the University of Bern has partnered with Swiss startup RocketVax to develop two live attenuated intranasal vaccine candidates against SARS-CoV-2 for planned Phase 1 trials. The consortium, which also includes researchers from the University of Geneva, the Freie Universität … [Read more...] about Consortium partners with RocketVax on intranasal COVID-19 vaccine development
TFF partners with US army on intranasal dry powder vaccine against SARS-CoV-2
TFF Pharmaceuticals said that the company has entered into an additional Cooperative Research and Development Agreement (CRADA) with the US Army Medical Research Institute of Infectious Diseases (USAMRIID) and the Geneva Foundation for formulation of an intranasal dry powder recombinant vesicular stomatitis virus (rVSV) against SARS-CoV-2 using … [Read more...] about TFF partners with US army on intranasal dry powder vaccine against SARS-CoV-2
Sandoz acquires inhaler developer Coalesce Product Development
Declaring that it is "determined to grow its portfolio in the complex generics space," Novartis generics division Sandoz announced its acquisition of device device developer Coalesce Product Development. Coalesce's inhaler technology include MDI, breath-actuated MDI, and DPI platforms. Sandoz said that it "sees respiratory as a key pillar of its ambitious long-term … [Read more...] about Sandoz acquires inhaler developer Coalesce Product Development
Aerami Therapeutics agreement with FoxWayne has been terminated
In December 2021, inhaled drug developer Aerami Therapeutics announced that it would go public by merging with FoxWayne Enterprises Acquisition Corp, a special purpose acquisition company (SPAC). The two companies have now announced that the deal is off, effective immediately, saying, "In light of current unfavorable market conditions, Aerami and FoxWayne believe that … [Read more...] about Aerami Therapeutics agreement with FoxWayne has been terminated
TFF Pharmaceuticals partners with Catalent for DPI development and manufacturing
TFF Pharmaceuticals has partnered with CDMO Catalent for scale-up and manufacturing of dry powder formulations based on TFF's thin film freezing technology the companies have announced. The partnership will make the TFF technology available to other Catalent clients as well. Catalent notes that the TFF technology is its second addition to its inhaled dry powder … [Read more...] about TFF Pharmaceuticals partners with Catalent for DPI development and manufacturing