Business

Alveolus Bio has received a 3-year Small Business Innovation Research (SBIR) FastTrack grant worth approximately $2.5 million from the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH) for development of an inhaled biotherapeutic for the treatment of COPD, the company said. The company's AB1000 inhaled live biotherapeutic … [Read more...] about Alveolus Bio gets $2.5 million SBIR FastTrack grant for development of inhaled live biotherapeutic

Spexis has announced a deal with SPRIM Global Investments (SGI) for funding of up to half of Spexis' costs related to Phase 3 development of ColiFin nebulized colistimethate sodium for the treatment of P. aeruginosa lung infections in patients with cystic fibrosis. Spexis was formed in December 2021 through a merger of Polyphor, which was developing inhaled … [Read more...] about Spexis gets funding for Phase 3 trials of ColiFin inhaled colistimethate sodium

Nonprofit biotech research institute Access to Advanced Health Institute (AAHI) said that it has received an award worth up to $9.9 million for a 40-month project aimed at development of liquid and dry powder versions of an intranasal influenza RNA vaccine candidate targeting the A(H5N1) and A(H7N9) avian influenza subtypes. The funding, which will support … [Read more...] about Access to Advanced Health Institute gets award worth up to $9.9 million for development of intranasal RNA flu vaccine

According to Liquidia, the US Patent Trial and Appeal Board (PTAB) has denied a request by United Therapeutics to revisit the board's July 2022 determination that none of the claims in US Patent No. 10,716,793, covering Tyvaso inhaled treprostinil, are patentable. Liquidia said that it expects United Therapeutics to appeal the denial of the rehearing to the US Court … [Read more...] about PTAB again supports Liquidia, denies United Therapeutics rehearing request for Tyvaso patent

Bharat Biotech has announced the launch of its iNCOVACC (BBV154) intranasal COVID vaccine in India for use as both primary series and booster. In September 2022, India's Central Drugs Standard Control Organization (CDSCO) approved the use of iNCOVACC in adults aged 18 and older. iNCOVACC is a recombinant replication-deficient adenovirus vectored vaccine that Bharat … [Read more...] about Bharat Biotech launches iNCOVACC intranasal COVID-19 vaccine in India

Adherium announced that it received an award of £499,871 for an inhaler monitoring project from Small Business Research Initiative (SBRI) Healthcare, a program from the UK's National Health Service. The project, titled "Smart Digital inhaler enabled asthma management in high-risk children aged 5 to 16 years managed in primary care to prevent asthma attacks," will … [Read more...] about Adherium gets almost £500,000 from SBRI Healthcare for inhaler monitoring project

Cambrian BioPharma announced that it has partnered with Aston University and Aston Professor Martin Griffin since 2019 on a startup called Isterian Biotech. According to the announcement, the company's pipeline features a transglutaminase 2 (TG2) inhibitor that has been shown to reduce lung fibrosis in a mouse model and which Isterian intends to develop as an inhaled … [Read more...] about Isterian Biotech to develop inhaled TG2 inhibitor for the treatment of IPF

Liquidia Corporation said that an investment by HealthCare Royalty (HCRx) of up to $100 million will support further clinical development and the potential launch of the company's Yutrepia treprostinil DPI. In return, HCRx will get tiered royalties on potential net revenue from Yutrepia and other Liquidia products in addition to fixed payments from Liquidia, with … [Read more...] about Liquidia announces financing agreement for up to $100 million