Inhalation Sciences AB (ISAB) has announced that the 3D module of its PreciseInhale dry powder aerosol testing system is now called “XposeALI.” Using air liquid interface (ALI) technology, ISAB creates 3D models with primary epithelial cells that allow for completion of a PK study using 50 – 100 mg of the test material, the company said.
ISAB CEO Fredrik Sjövall commented, “Even our nearest competitors in cell exposures have limitations that we overcome by combining ALI with our dry powder aerosolization platform PreciseInhale. Limited in handling dry powders, they primarily use nebulized droplets instead – so they are unlikely to achieve the deposition quality XposeALI delivers. Today these competing technologies essentially generate static PK data, not dynamic data that includes Cmax and Tmax curves, as ours does. XposeALI is still in development but maturing rapidly and earning a great deal of recognition.”
Read the ISAB press release.