Copley Scientific has announced the launch of its BAC 2000 breath actuated controller and BRS 1100 breathing simulator for the testing of MDIs with spacers and valved holding chambers in accordance with draft US Pharmacopoeia (USP) monograph <1602>. Together, the breath actuated controller and breathing simulator provide testing conditions representative of a range of patient ages, including neonates and infants, as specified in the monograph.
According to Copley, the BAC 2000 can be set to delay the start of flow until a specific amount of time after actuation of the MDI and can also be set for a defined amount of inhalation time. The actuator can be used for both cascade impaction and dose uniformity testing.
The BRS 1100 can generate breathing profiles for dose uniformity testing of MDIs with spacers and holding chambers or for nebulizer testing. Tidal volume, frequency, duration, and inhalation/exhalation ratio can be set to generate breathing profiles, and the breathing cycle can be set to start at either inhalation or exhalation.
Read the Copley Scientific press release.
