Melbourn Scientific is now offering powder characterization services using the Freeman Technology FT4 Powder Rheometer to optimize formulation and analysis services for inhaled drug and device development.
Melbourn Scientific Operations Director Derek Solomon commented, “A key challenge of developing pharmaceuticals for inhalation is creating a formulation that offers both good pharmacologic activity and desirable pharmaceutical properties – fluidity, dispersion, delivery and deposition. It is becoming more widely understood that powder properties can vary widely with different formulations and this can impact the performance of a DPI. Use of specialist equipment, such as the FT4, makes it possible to characterise the powder and optimize the formulation.”
Freeman Technology Operations Manager, Jamie Clayton added, “The FT4 provides an innovative and patented approach to powder testing that quantifies dynamic properties (flow energy, stability, aeration) bulk properties (permeability, compressibility) and shear properties. For the first time this allows sensitive and reliable characterisation of powders with respect to a given process, which helps improve quality control and performance from development through to manufacture.”
Melbourn offers a wide range of testing services for OINDP development.