A Massachusetts engineering firm called Enginasion has disclosed details of proprietary DPI-filling technology it says that it developed for a pharmaceutical client that needed accurate dispensing of a highly cohesive inhaled dry powder formulation into cartridges. Enginasion Founder and CEO David Bonneau is the co-author of several patents assigned to MannKind Corporation that describe a dispensing system for MannKind’s Technosphere dry powder formulations.
Bonneau describes the system as using 48 microbalances for 50 mcg dispensing accuracy and 100% inspection within a cubic foot of space. He claims that “For the first time, every single dosage can be inspected to ensure the dispensing of the precise amount of dry powder.”
View an image of the system with audio description. (link may not work in all browsers)
View patent.
Read the Enginasion press release.